Cisplatin electrolyte abnormalities

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August undefined, 2024

WebSep 15, 2024 · Cisplatin is administered parenterally and is available in 50 and 100 mg vials in generic forms and under the brand name Platinol. The recommended dose varies by indication, tumor type, patient age and body weight. Common side effects include nausea, vomiting, bone marrow suppression, electrolyte imbalance, neuropathy, ototoxicity and ... Webmay drive unique electrolyte disorders in different malignancies. In the next sections, the clinical fea-tures, pathophysiology, and treatment of the most …

Amphotericin B nephrotoxicity - UpToDate

WebDec 16, 2024 · However, cisplatin-induced nephrotoxicity is a major dose-limiting factor and a significant adverse event. Mannitol is used to reduce cisplatin-induced nephrotoxicity, which is controversial. ... Diuretics contribute to electrolyte disorders, often promoting the excretion of electrolytes into urine by the kidneys. In this meta … WebHypomagnesemia may cause nausea, vomiting, sleepiness, weakness, personality changes, muscle spasms, tremors, and loss of appetite. If severe, hypomagnesemia can cause seizures Seizure Disorders In seizure disorders, the brain's electrical activity is periodically disturbed, resulting in some degree of temporary brain dysfunction. Many … share the love hoodie

Acute kidney injury during cisplatin therapy and …

WebNov 1, 2024 · Special attention needs to be paid to electrolyte disturbances, which should be particularly considered when administering high doses of cisplatin [19]. The most common electrolyte disorder is ... http://www.ejmanager.com/mnstemps/93/93-1446132625.pdf#:~:text=The%20most%20common%20electrolyte%20abnormality%20associated%20with%20cisplatin,the%20incidence%20of%20which%20varies%20significantly%20between%20studies. Web• Hypomagnesemia and Accompanying Electrolyte Abnormalities: Monitor during treatment and for at least 8 weeks following the completion. Replete electrolytes as necessary. (5.6) ... and Cisplatin . 5.6 Hypomagnesemia and Accompanying Electrolyte Abnormalities . 5.7 Increased Tumor Progression, Increased Mortality, or Lack ... poplar heights pool falls church

Cancer Treatment–Induced Arrhythmias Circulation: Arrhythmia …

Cisplatin induced arrhythmia; electrolyte imbalance or disturbance …

WebDec 29, 2024 · Anticancer agents associated with electrolyte abnormalities included cisplatin, carboplatin, oxaliplatin, vincristine, vinblastine, cyclophosphamide and ifosfamide. CKD, chronic kidney disease. Open in new tab Incidence of hyponatremia and other electrolyte abnormalities WebNational Center for Biotechnology Information share the love game master in the woodsWebSep 15, 2024 · Cisplatin's side effects primarily include nephrotoxicity, gastrointestinal toxicity, neurotoxicity and ototoxicity. Cardiotoxicity is generally not defined as a side … share the love family

"WebSep 27, 2024 · Nephrotoxicity: cisplatin for injection can cause severe renal toxicity, including acute renal failure. Severe renal toxicities are dose-related and cumulative. Ensure adequate hydration and monitor renal function and electrolytes. " - Cisplatin electrolyte abnormalities

Cisplatin electrolyte abnormalities

WebJun 8, 2024 · Cisplatin injection can cause dose-related peripheral neuropathy that becomes more severe with repeated courses of the drug. Neurologic symptoms have … WebSep 1, 2024 · Cisplatin for injection can cause severe hypersensitivity reactions, including anaphylaxis and death. Manifestations have included facial edema, wheezing, …

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WebDec 9, 2024 · Electrolyte disorders are very common conditions in cancer patients. They mainly concern changes in serum sodium, potassium, calcium, and magnesium levels. In most cases, these alterations are asymptomatic and therefore not always taken into consideration in clinical practice.

WebMay 1, 2024 · The most common diagnoses were central nervous system tumors (58 [36%]), neuroblastoma (43 [27%]), and osteosarcoma (33 [21%]). Acute kidney injury (by serum creatinine level increase) occurred in 48 of 159 patients (30%) at early cisplatin infusions and 23 of 143 patients (16%) at late cisplatin infusions. WebMar 1, 2024 · A case of an elderly male presenting with significant recurrent hyponatremia, and prerenal azotemia, with recent exposure to cisplatin along with significant hypovolemia and urinary loss of sodium is reported. Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude …

WebOct 19, 2024 · Severe electrolyte abnormalities (secondary exposure) included ≥ grade three hypophosphatemia, hypokalemia, or hypomagnesemia (National Cancer Institute Common Terminology Criteria for Adverse Events v4.0). CKD was albuminuria or decreased kidney function for age (KDIGO guidelines). WebMay 24, 2006 · This drug should be considered among the possible causes of chronic unexplained electrolyte disorders. Cisplatin is a well-known nephrotoxic antineoplastic …

WebElectrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia, …

WebCisplatin can cause increased magnesium losses by the kidneys as well as generalized decrease in kidney function. Magnesium loses can be severe and persist despite discontinuation of cisplatin. Discontinuation of cisplatin is still recommended if signs of renal toxicity occur during therapy. Table Causes of Hypomagnesemia share the love gifWebApr 15, 2016 · 3. Platinum-containing drugs (cisplatin, carboplatin and oxaliplatin) Cisplatin, carboplatin and oxaliplatin are platinum-containing anticancer drugs targeting solid cancers, such as head and neck cancer, lung cancer, and cervical cancer (Ali et al., 2013).The use of these drugs has been associated with a number of electrolyte … poplar heights recreation associationWebCisplatin is widely used in the treatment of multiple cancers, including metastatic gonadal tumors and advanced bladder cancer. ... Some cases of ventricular fibrillation have occurred in the setting of documented electrolyte abnormalities that can develop right after amsacrine administration. 85 The importance of maintaining electrolyte ... poplar hedge farmWeb5.3 Electrolyte and Metabolic Abnormalities In addition to causing hyperkalemia, spironolactone tablets can cause hyponatremia, hypomagnesemia, hypocalcemia, hypochloremic alkalosis, and hyperglycemia. Asymptomatic hyperuricemia can occur and rarely gout is precipitated. Monitor serum electrolytes, uric acid and blood glucose … share the love heartWebOct 19, 2024 · In the literature, cisplatin-associated electrolyte abnormalities are poorly described, but hypomagnesemia occurs in 14–94% of children [3, 4, 36, 38, 39]. CNS … share the land songWebJul 28, 2024 · Electrolyte Abnormalities: This medication can affect the normal levels of electrolytes (potassium, magnesium, calcium, etc.) in your body. Your levels will be monitored using blood tests. If your levels become too low, your care team may prescribe specific electrolytes to be given by IV or taken by mouth. share the love hoodie amazonWebSep 18, 2024 · NCBI Bookshelf share the love invite your friends