WebAug 13, 2012 · Results: We found that BV2 microglia readily phagocytosed apoptotic PC12 cells, but this was inhibited by a CRT-blocking antibody or LRP-blocking protein … WebAntibodies that detect Alexa Fluor 488 can be used in several scientific applications, including Flow Cytometry, Fluorescent Quenching, Immunocytochemistry and Immunohistochemistry. Our Alexa Fluor 488 polyclonal and recombinant polyclonal antibodies are developed in Rabbit.
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WebDec 30, 2014 · CRT normally is an endoplasmic reticulum (ER) protein possessing ER retention KDEL sequences but can be released to the cell surface in many instances of cell damage by cytotoxic drugs or inflammation and is recognized by macrophage LRP1/CD91 during phagocytosis of apoptotic cells ( 12, 13 ). WebJul 15, 2013 · Background: Calreticulin (CRT) is a chaperone protein, which aids correct folding of glycosylated proteins in the endoplasmic reticulum (ER). Under conditions of ER stress, CRT is upregulated and may be displayed on the surface of cells or be secreted. tawuran sma 6 dan 70
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WebIn order to characterize CrT protein(s) on a biochemical level, antibodies were raised against synthetic peptides derived from the N- and C-terminal cDNA sequences of the putative CrT-1 protein. In total homogenates of various tissues, both antibodies, directed against these different epitopes, recognize the same two major polypetides on ... WebJun 4, 2024 · Another report showed that gold nanoclusters conjugated to an anti-CRT antibody could be used as a probe for near-infrared imaging to detect ecto-CRT in HT-29 colorectal cancer cells . Our monobodies bound to CRT with a binding affinity comparable with that of the antibody and were more stable in serum than the peptides. Upon … WebCRT can bind to CD91/lRP1, a receptor on the surface of innate immune cells, such as macrophages, dendritic cells and other immune cells, to enhance the immune response. 12 In addition, studies have shown that high concentrations of CRT and its antibodies can be detected in the serum of rheumatoid or SLE patients, suggesting that CRT is related ... tawuran sma70