Shank2 gene in hcc

Author: giss

August undefined, 2024

WebbSHANK2. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 1849. Protein existence. Evidence at protein level. Annotation score. 5/5. … Webb8 juli 2024 · DYNLL2, H2AFJ, SHANK2, ZWILCH, CDC14A, IFT20, MTA3, SERPINA1 and TCF4 were confirmed as key genes in this process. Moreover, our study showed Akt …

Genetic Analysis Implicates Dysregulation of SHANK2 in Renal …

WebbLeblond et al, 2014 performed a meta-analysis of the SHANK gene (SHANK1, SHANK2, SHANK3) copy number and coding sequencing variants in patients with ASD in order to … Webb14 juni 2012 · Shank2 (also known as ProSAP1) is a multi-domain scaffolding protein and signalling adaptor enriched at excitatory neuronal synapses, and mutations in the human SHANK2 gene have recently been... how do you add people on google chat

VCV000006516.1 - ClinVar - NCBI

Webb4 apr. 2024 · Several studies aimed to construct effective predictive models in HCC previously, including deep learning-based multi-omics model, radiomics model and gene signature models [2–6]. Studies have proved that m6A-related genes, ferroptosis-related genes, and aging-related genes were all associated with cancer prognosis [ 7 , 8 ]. WebbBesides, RAB7A was a multi-pathway target involved in the malignant progression of HCC. Lipophagy-related gene RAB7A is involved in immune regulation and malignant progression in hepatocellular carcinoma Comput Biol Med. 2024 Apr 6;158:106862. doi: 10.1016/j.compbiomed.2024.106862. ... WebbThis gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular sca ffolds in the postsynaptic density of excitatory synapses. … ph value of banana

A novel NHEJ gene signature based model for risk stratification …

Bioinformatics analysis revealed hub genes and pathways …

WebbSHANK2 Gene - Somatic Mutations in Cancer Gene GRCh38 · CELL LINES v97 Gene view The gene view histogram is a graphical view of mutations across SHANK2. These … WebbA pooled analysis of public gene expression datasets showed downregulation of SHANK2 in kidney cancer specimens, suggesting that this gene might play an important role … how do you add people on prodigy math gameWebbREVIEW published: 19 July 2024 doi: 10.3389/fnmol.2024.00240 Distinct Phenotypes of Shank2 Mouse Models Reﬂect Neuropsychiatric Spectrum Disorders of Human Patients With how do you add people on minecraft

"Webb12 apr. 2024 · Lung cancer is a highly heterogeneous disease. Cancer cells and other cells within the tumor microenvironment interact to determine disease progression, as well as response to or escape from treatment. Understanding the regulatory relationship between cancer cells and their tumor microenvironment in lung adenocarcinoma is of great … " - Shank2 gene in hcc

Shank2 gene in hcc

SHANK2 protein expression summary - The Human Protein Atlas

WebbFor the HCC set, the most-observed (top-1) gene PPIA has been characterized as a biomarker for the diagnosis of liver cancer under a patent Publication Number "US20100203510 A1". WebbSHANK2 is part of cluster 88 Choroid plexus - Transmembrane transport with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated …

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WebbSHANK family proteins (SHANK1, SHANK2, & SHANK3) have emerged as promising candidates for modeling ASD in mice due to strong genetic evidence showing … Webb7 maj 2024 · Although rare, chromothripsis, multiple structural rearrangements in single catastrophic mitosis, was also reported in HCC [ 5 ]. A broad range of cancer-related …

Webb7 apr. 2024 · Sasaki et al. demonstrate that epithelial Shank2 localizes at tight junctions (TJs) via its epithelia-specific N terminus and interacts with aPKC. Through small … WebbNo SHANK2 duplications were found in patients with ASD. SHANK3 gene, located on chromosome 22q13.3, has 22 exons that codify for an extensive number of mRNA and …

WebbAbout 0:00 on April 12, 2013, after the police determined that Lin was a suspect and summoned him, Lin then confessed that he had put N-nitrosodimethylamine in dorm … WebbSHANK2 SHANK2 mutations are associated with autism spectrum disorder (ASD), moderate ID, developmental delay, and mild motor deficits. From: Neuronal and Synaptic …

Webb27 juni 2012 · By genomewide microarray scan for copy number variants (CNV) in a German cohort of 184 unrelated individuals with mental retardation and a series of 396 …

WebbThe alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank … how do you add people on outlookWebb25 mars 2024 · The transcriptome in isogenic SHANK2 neurons was perturbed in synapse, plasticity, and neuronal morphogenesis gene sets and ASD gene modules, and activity … ph value of alcoholWebbThe SHANK3 gene provides instructions for making a protein that is found in many of the body's tissues but is most abundant in the brain. The SHANK3 protein plays a role in the … how do you add people on robloxWebbGenetic CategoryRare Single Gene Mutation, Syndromic, Genetic Association, Functional. Rare SHANK2 deletions have been identified in ASD cases, but not in controls (PMIDs … ph value of appleWebbDownload scientific diagram SHANK2 expression is mostly restricted to the neuronal system. (A) SHANK2 expression in adult mice tissues determined by Western blot. (B) … ph value of barium hydroxideWebb15 maj 2004 · The present study utilized bioinformatics to demonstrate the presence of exons encoding ankyrin repeats in the region preceding the previously described Shank2 gene. cDNA sequencing of mRNA from epithelial cells revealed a novel spliceoform of Shank2, termed Shank2E, that encodes a predicted 200 kDa protein with six N-terminal … ph value of bee stingWebb25 sep. 2024 · Genetic defects in the SHANK2 gene, encoding for synaptic scaffolding protein, are associated with a variety of neurodevelopmental conditions, including autism spectrum disorders and mild to... ph value of beer